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DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer. Indeed, high-penetrance germline mutations in DNA repair genes are important players in familial cancers: BRCA1, BRCA2 mutations or mismatch repai...

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Detalles Bibliográficos
Autores principales:	Tomasova, Kristyna, Cumova, Andrea, Seborova, Karolina, Horak, Josef, Koucka, Kamila, Vodickova, Ludmila, Vaclavikova, Radka, Vodicka, Pavel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408288/ https://www.ncbi.nlm.nih.gov/pubmed/32605254 http://dx.doi.org/10.3390/cancers12071713

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