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Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models

Ciliary neurotrophic factor (CNTF) is one of the most studied neuroprotective agents with acknowledged potential in treating diseases of the posterior eye segment. Although its efficacy and mechanisms of action in the retina have been studied extensively, it is still not comprehensively understood w...

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Detalles Bibliográficos
Autores principales:	Itkonen, Jaakko, Annala, Ada, Tavakoli, Shirin, Arango-Gonzalez, Blanca, Ueffing, Marius, Toropainen, Elisa, Ruponen, Marika, Casteleijn, Marco G., Urtti, Arto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408322/ https://www.ncbi.nlm.nih.gov/pubmed/32629980 http://dx.doi.org/10.3390/pharmaceutics12070611

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