Tissue Levels of Flurbiprofen in the Rat Plantar Heel after Short-Duration Topical Iontophoresis Are Sufficient to Induce Pharmacodynamic Responses to Local Pain Stimuli

The objective of this study was to investigate the topical iontophoresis of flurbiprofen (FBF) as a means to enhance its local bioavailability and thereby provide an improved and targeted treatment of plantar heel pain. Initial in vitro experiments using porcine ear skin investigated iontophoretic t...

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Detalles Bibliográficos
Autores principales: Cai, Yilu, Zhou, Ye, Zhang, Peiyan, Kalia, Yogeshvar N., Gratieri, Tais, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408369/
https://www.ncbi.nlm.nih.gov/pubmed/32629832
http://dx.doi.org/10.3390/pharmaceutics12070608

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