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Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility

UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea. This protein couples the hydrolysis of GTP to the delivery of Ni(II) into the active site of apo-urease, interacting with other urease chaperones...

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Detalles Bibliográficos
Autores principales: Pierro, Annalisa, Etienne, Emilien, Gerbaud, Guillaume, Guigliarelli, Bruno, Ciurli, Stefano, Belle, Valérie, Zambelli, Barbara, Mileo, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408563/
https://www.ncbi.nlm.nih.gov/pubmed/32708696
http://dx.doi.org/10.3390/biom10071062