Impacts of High Intra- and Inter-Individual Variability in Tacrolimus Pharmacokinetics and Fast Tacrolimus Metabolism on Outcomes of Solid Organ Transplant Recipients

Tacrolimus is a first-line calcineurin inhibitor (CNI) and an integral part of the immunosuppressive strategy in solid organ transplantation. Being a dose-critical drug, tacrolimus has a narrow therapeutic index that necessitates periodic monitoring to maintain the drug’s efficacy and reduce the con...

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Detalles Bibliográficos
Autores principales: Thongprayoon, Charat, Hansrivijit, Panupong, Kovvuru, Karthik, Kanduri, Swetha R., Bathini, Tarun, Pivovarova, Aleksandra, Smith, Justin R., Cheungpasitporn, Wisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408675/
https://www.ncbi.nlm.nih.gov/pubmed/32664531
http://dx.doi.org/10.3390/jcm9072193

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