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Kurarinone Inhibits HCoV-OC43 Infection by Impairing the Virus-Induced Autophagic Flux in MRC-5 Human Lung Cells

Kurarinone is a prenylated flavonone isolated from the roots of Sophora flavescens. Among its known functions, kurarinone has both anti-apoptotic and anti-inflammatory properties. Coronaviruses (CoVs), including HCoV-OC43, SARS-CoV, MERS-CoV, and SARS-CoV-2, are the causative agents of respiratory v...

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Detalles Bibliográficos
Autores principales: Min, Jung Sun, Kim, Dong Eon, Jin, Young-Hee, Kwon, Sunoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408680/
https://www.ncbi.nlm.nih.gov/pubmed/32674356
http://dx.doi.org/10.3390/jcm9072230