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ACE2 as a Therapeutic Target for COVID-19; Its Role in Infectious Processes and Regulation by Modulators of the RAAS System

Angiotensin converting enzyme 2 (ACE2) is the recognized host cell receptor responsible for mediating infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 bound to tissue facilitates infectivity of SARS-CoV-2; thus, one could argue that decreasing ACE2 tissue expression wo...

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Detalles Bibliográficos
Autores principales: Michaud, Veronique, Deodhar, Malavika, Arwood, Meghan, Al Rihani, Sweilem B, Dow, Pamela, Turgeon, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408699/
https://www.ncbi.nlm.nih.gov/pubmed/32635289
http://dx.doi.org/10.3390/jcm9072096