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TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis

The short isoform of human TIAM2 has been shown to promote proliferation and invasion in various cancer cells. However, the roles of TIAM2S in immune cells in relation to tumor development have not been investigated. To characterize the effects of TIAM2S, we generated TIAM2S-overexpressing mouse lin...

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Detalles Bibliográficos
Autores principales: Chan, Ya-Ling, Lai, Wei-Chung, Chen, Jia-Shing, Tseng, Joseph Ta-Chien, Chuang, Pei-Chin, Jou, Jonathan, Lee, Chung-Ta, Sun, H. Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408714/
https://www.ncbi.nlm.nih.gov/pubmed/32650570
http://dx.doi.org/10.3390/cancers12071844