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Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to diff...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408846/ https://www.ncbi.nlm.nih.gov/pubmed/32650555 http://dx.doi.org/10.3390/jcm9072161 |
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author | Trevor, Lucy V Riches-Suman, Kirsten Mahajan, Ajay L Thornton, M Julie |
author_facet | Trevor, Lucy V Riches-Suman, Kirsten Mahajan, Ajay L Thornton, M Julie |
author_sort | Trevor, Lucy V |
collection | PubMed |
description | Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing. |
format | Online Article Text |
id | pubmed-7408846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74088462020-08-13 Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing Trevor, Lucy V Riches-Suman, Kirsten Mahajan, Ajay L Thornton, M Julie J Clin Med Review Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing. MDPI 2020-07-08 /pmc/articles/PMC7408846/ /pubmed/32650555 http://dx.doi.org/10.3390/jcm9072161 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Trevor, Lucy V Riches-Suman, Kirsten Mahajan, Ajay L Thornton, M Julie Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title | Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title_full | Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title_fullStr | Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title_full_unstemmed | Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title_short | Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing |
title_sort | adipose tissue: a source of stem cells with potential for regenerative therapies for wound healing |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408846/ https://www.ncbi.nlm.nih.gov/pubmed/32650555 http://dx.doi.org/10.3390/jcm9072161 |
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