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Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing

Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to diff...

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Detalles Bibliográficos
Autores principales: Trevor, Lucy V, Riches-Suman, Kirsten, Mahajan, Ajay L, Thornton, M Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408846/
https://www.ncbi.nlm.nih.gov/pubmed/32650555
http://dx.doi.org/10.3390/jcm9072161
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author Trevor, Lucy V
Riches-Suman, Kirsten
Mahajan, Ajay L
Thornton, M Julie
author_facet Trevor, Lucy V
Riches-Suman, Kirsten
Mahajan, Ajay L
Thornton, M Julie
author_sort Trevor, Lucy V
collection PubMed
description Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing.
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spelling pubmed-74088462020-08-13 Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing Trevor, Lucy V Riches-Suman, Kirsten Mahajan, Ajay L Thornton, M Julie J Clin Med Review Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing. MDPI 2020-07-08 /pmc/articles/PMC7408846/ /pubmed/32650555 http://dx.doi.org/10.3390/jcm9072161 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Trevor, Lucy V
Riches-Suman, Kirsten
Mahajan, Ajay L
Thornton, M Julie
Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title_full Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title_fullStr Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title_full_unstemmed Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title_short Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing
title_sort adipose tissue: a source of stem cells with potential for regenerative therapies for wound healing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408846/
https://www.ncbi.nlm.nih.gov/pubmed/32650555
http://dx.doi.org/10.3390/jcm9072161
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