Sjögren’s Syndrome Minor Salivary Gland CD4(+) Memory T Cells Associate with Glandular Disease Features and Have a Germinal Center T Follicular Helper Transcriptional Profile

To assess the types of salivary gland (SG) T cells contributing to Sjögren’s syndrome (SS), we evaluated SG T cell subtypes for association with disease features and compared the SG CD4(+) memory T cell transcriptomes of subjects with either primary SS (pSS) or non-SS sicca (nSS). SG biopsies were e...

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Detalles Bibliográficos
Autores principales: Joachims, Michelle L., Leehan, Kerry M., Dozmorov, Mikhail G., Georgescu, Constantin, Pan, Zijian, Lawrence, Christina, Marlin, M. Caleb, Macwana, Susan, Rasmussen, Astrid, Radfar, Lida, Lewis, David M., Stone, Donald U., Grundahl, Kiely, Scofield, R. Hal, Lessard, Christopher J., Wren, Jonathan D., Thompson, Linda F., Guthridge, Joel M., Sivils, Kathy L., Moore, Jacen S., Farris, A. Darise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408878/
https://www.ncbi.nlm.nih.gov/pubmed/32650575
http://dx.doi.org/10.3390/jcm9072164

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