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Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review

The prognostic value of “snake-eyes” sign in spinal cord magnetic resonance imaging (MRI) is unclear and the correlation with different pathological conditions has not been completely elucidated. In addition, its influence on surgical outcome has not been investigated in depth. A literature review a...

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Autores principales: Fontanella, Marco Maria, Zanin, Luca, Bergomi, Riccardo, Fazio, Marco, Zattra, Costanza Maria, Agosti, Edoardo, Saraceno, Giorgio, Schembari, Silvia, De Maria, Lucio, Quartini, Luisa, Leggio, Ugo, Filosto, Massimiliano, Gasparotti, Roberto, Locatelli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408892/
https://www.ncbi.nlm.nih.gov/pubmed/32664657
http://dx.doi.org/10.3390/jcm9072197
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author Fontanella, Marco Maria
Zanin, Luca
Bergomi, Riccardo
Fazio, Marco
Zattra, Costanza Maria
Agosti, Edoardo
Saraceno, Giorgio
Schembari, Silvia
De Maria, Lucio
Quartini, Luisa
Leggio, Ugo
Filosto, Massimiliano
Gasparotti, Roberto
Locatelli, Davide
author_facet Fontanella, Marco Maria
Zanin, Luca
Bergomi, Riccardo
Fazio, Marco
Zattra, Costanza Maria
Agosti, Edoardo
Saraceno, Giorgio
Schembari, Silvia
De Maria, Lucio
Quartini, Luisa
Leggio, Ugo
Filosto, Massimiliano
Gasparotti, Roberto
Locatelli, Davide
author_sort Fontanella, Marco Maria
collection PubMed
description The prognostic value of “snake-eyes” sign in spinal cord magnetic resonance imaging (MRI) is unclear and the correlation with different pathological conditions has not been completely elucidated. In addition, its influence on surgical outcome has not been investigated in depth. A literature review according to PRISMA (Preferred reporting items for systematic review and meta-analysis protocols) guidelines on the prognostic significance of “snake-eyes” sign in operated patients was performed. Clinical, neuroradiological, and surgical data of three institutional patients, were also retrospectively collected. The three patients, with radiological evidence of “snake-eyes” myelopathy, underwent appropriate surgical treatment for their condition, with no new post-operative neurological deficits and good outcome at follow-up. The literature review, however, reported conflicting results: the presence of “snake-eyes” sign seems a poor prognostic factor in degenerative cervical myelopathy, even if some cases can improve after surgery. “Snake-eyes” myelopathy represents a rare form of myelopathy; pathophysiology is still unclear. The frequency of this myelopathy may be greater than previously thought and according to our literature review it is mostly a negative prognostic factor. However, from our experience, prognosis might not be so dire, especially when tailored surgical intervention is performed; therefore, surgery should always be considered and based on the complete clinical, neurophysiological, and radiological data.
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spelling pubmed-74088922020-08-13 Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review Fontanella, Marco Maria Zanin, Luca Bergomi, Riccardo Fazio, Marco Zattra, Costanza Maria Agosti, Edoardo Saraceno, Giorgio Schembari, Silvia De Maria, Lucio Quartini, Luisa Leggio, Ugo Filosto, Massimiliano Gasparotti, Roberto Locatelli, Davide J Clin Med Review The prognostic value of “snake-eyes” sign in spinal cord magnetic resonance imaging (MRI) is unclear and the correlation with different pathological conditions has not been completely elucidated. In addition, its influence on surgical outcome has not been investigated in depth. A literature review according to PRISMA (Preferred reporting items for systematic review and meta-analysis protocols) guidelines on the prognostic significance of “snake-eyes” sign in operated patients was performed. Clinical, neuroradiological, and surgical data of three institutional patients, were also retrospectively collected. The three patients, with radiological evidence of “snake-eyes” myelopathy, underwent appropriate surgical treatment for their condition, with no new post-operative neurological deficits and good outcome at follow-up. The literature review, however, reported conflicting results: the presence of “snake-eyes” sign seems a poor prognostic factor in degenerative cervical myelopathy, even if some cases can improve after surgery. “Snake-eyes” myelopathy represents a rare form of myelopathy; pathophysiology is still unclear. The frequency of this myelopathy may be greater than previously thought and according to our literature review it is mostly a negative prognostic factor. However, from our experience, prognosis might not be so dire, especially when tailored surgical intervention is performed; therefore, surgery should always be considered and based on the complete clinical, neurophysiological, and radiological data. MDPI 2020-07-12 /pmc/articles/PMC7408892/ /pubmed/32664657 http://dx.doi.org/10.3390/jcm9072197 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Fontanella, Marco Maria
Zanin, Luca
Bergomi, Riccardo
Fazio, Marco
Zattra, Costanza Maria
Agosti, Edoardo
Saraceno, Giorgio
Schembari, Silvia
De Maria, Lucio
Quartini, Luisa
Leggio, Ugo
Filosto, Massimiliano
Gasparotti, Roberto
Locatelli, Davide
Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title_full Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title_fullStr Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title_full_unstemmed Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title_short Snake-Eye Myelopathy and Surgical Prognosis: Case Series and Systematic Literature Review
title_sort snake-eye myelopathy and surgical prognosis: case series and systematic literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408892/
https://www.ncbi.nlm.nih.gov/pubmed/32664657
http://dx.doi.org/10.3390/jcm9072197
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