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CCR2 of Tumor Microenvironmental Cells Is a Relevant Modulator of Glioma Biology

Glioblastoma multiforme (GBM) shows a high influx of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is considered a relevant signal for the recruitment of TAMs and has been suggested as a therapeutic target in malignant gliomas. We found that TAMs of human GBM specimens and of a syngenei...

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Detalles Bibliográficos
Autores principales: Felsenstein, Matthäus, Blank, Anne, Bungert, Alexander D., Mueller, Annett, Ghori, Adnan, Kremenetskaia, Irina, Rung, Olga, Broggini, Thomas, Turkowski, Kati, Scherschinski, Lea, Raggatz, Jonas, Vajkoczy, Peter, Brandenburg, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408933/
https://www.ncbi.nlm.nih.gov/pubmed/32668709
http://dx.doi.org/10.3390/cancers12071882