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CCR2 of Tumor Microenvironmental Cells Is a Relevant Modulator of Glioma Biology
Glioblastoma multiforme (GBM) shows a high influx of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is considered a relevant signal for the recruitment of TAMs and has been suggested as a therapeutic target in malignant gliomas. We found that TAMs of human GBM specimens and of a syngenei...
Autores principales: | Felsenstein, Matthäus, Blank, Anne, Bungert, Alexander D., Mueller, Annett, Ghori, Adnan, Kremenetskaia, Irina, Rung, Olga, Broggini, Thomas, Turkowski, Kati, Scherschinski, Lea, Raggatz, Jonas, Vajkoczy, Peter, Brandenburg, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408933/ https://www.ncbi.nlm.nih.gov/pubmed/32668709 http://dx.doi.org/10.3390/cancers12071882 |
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