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Peptidyl Arginine Deiminase Type 4 Gene Promoter Hypo-Methylation in Rheumatoid Arthritis
Protein citrullination is carried out by peptidylarginine deiminase type 4 (PAD4) enzyme. As a consequence of this process, post-translationally modified proteins are formed that become antigens for anti-citrullinated protein antibodies (ACPA). The study aimed at identifying whether the PADI4 gene i...
Autores principales: | Kolarz, Bogdan, Ciesla, Marek, Dryglewska, Magdalena, Majdan, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408948/ https://www.ncbi.nlm.nih.gov/pubmed/32629762 http://dx.doi.org/10.3390/jcm9072049 |
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