Genomic and Transcriptomic Characterisation of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Standard treatment for locally advanced rectal cancer (LARC) is neoadjuvant chemoradiotherapy (NACRT), followed by surgical resection. However, >70% of patients do not achieve a complete pathological response and have higher rates of relapse and death. There are no validated pre- or on-treatment...

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Detalles Bibliográficos
Autores principales: Toomey, Sinead, Gunther, Jillian, Carr, Aoife, Weksberg, David C., Thomas, Valentina, Salvucci, Manuela, Bacon, Orna, Sherif, El-Masry, Fay, Joanna, Kay, Elaine W., Sheehan, Katherine M., McNamara, Deborah A., Sanders, Keith L, Mathew, Geena, Breathnach, Oscar S., Grogan, Liam, Morris, Patrick G., Foo, Wai C., You, Yi-Qian N., Prehn, Jochen H., O’Neill, Brian, Krishnan, Sunil, Hennessy, Bryan T., Furney, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408989/
https://www.ncbi.nlm.nih.gov/pubmed/32640573
http://dx.doi.org/10.3390/cancers12071808

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