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Large-Scale Drug Screen Identifies FDA-Approved Drugs for Repurposing in Sickle-Cell Disease

Sickle-cell disease (SCD) is a debilitating hematological disorder with very few approved treatment options. Therapeutic reactivation of fetal hemoglobin (HbF) is one of the most pursued methods for ameliorating the systemic manifestations of SCD. Despite this, very few pharmacological agents have a...

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Detalles Bibliográficos
Autores principales: Cannon, Matthew, Phillips, Hannah, Smith, Sidney, Williams, Katie, Brinton, Lindsey, Gregory, Charles, Landes, Kristina, Desai, Payal, Byrd, John, Lapalombella, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408993/
https://www.ncbi.nlm.nih.gov/pubmed/32708954
http://dx.doi.org/10.3390/jcm9072276