Cargando…

The Therapeutic Potential of Targeting BARF1 in EBV-Associated Malignancies

Epstein-Barr virus (EBV) is closely linked to the development of a number of human cancers. EBV-associated malignancies are characterized by a restricted pattern of viral latent protein expression which is sufficient for the virus to both initiate and sustain cell growth and to protect virus-infecte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo, Angela Kwok-Fung, Dawson, Christopher W., Lung, Hong Lok, Wong, Ka-Leung, Young, Lawrence S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409022/ https://www.ncbi.nlm.nih.gov/pubmed/32708965 http://dx.doi.org/10.3390/cancers12071940

Ejemplares similares

The Role of EBV-Encoded LMP1 in the NPC Tumor Microenvironment: From Function to Therapy
por: Lo, Angela Kwok-Fung, et al.
Publicado: (2021)

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors
por: Turrini, Riccardo, et al.
Publicado: (2017)

Combination of the LEP II f \barf Results
por: LEPEWWG ff Subgroup
Publicado: (2018)

Sequence analysis of Epstein-Barr virus (EBV) early genes BARF1 and BHRF1 in NK/T cell lymphoma from Northern China
por: Sun, Lingling, et al.
Publicado: (2015)

EBV‐encoded miRNAs target ATM‐mediated response in nasopharyngeal carcinoma
por: Lung, Raymond W‐M, et al.
Publicado: (2018)

EBV latent membrane protein 1 augments γδ T cell cytotoxicity against nasopharyngeal carcinoma by induction of butyrophilin molecules
por: Liu, Yue, et al.
Publicado: (2023)

EBV–encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1
por: Lung, Raymond Wai‐Ming, et al.
Publicado: (2020)

Tumor Molecular and Microenvironment Characteristics in EBV-Associated Malignancies as Potential Therapeutic Targets: Focus on Gastric Cancer
por: Atri-Schuller, Aviva, et al.
Publicado: (2022)

Targeting Epstein-Barr Virus in Nasopharyngeal Carcinoma
por: Hau, Pok Man, et al.
Publicado: (2020)

SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target
por: Emanuel, Oscar, et al.
Publicado: (2021)

Activation of sterol regulatory element‐binding protein 1 (SREBP1)‐mediated lipogenesis by the Epstein–Barr virus‐encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma
por: Lo, Angela Kwok‐Fung, et al.
Publicado: (2018)

EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers
por: Jiang, Lijun, et al.
Publicado: (2018)

Selection of the Channel e^+e^- -> H^0Z0-> f\barf\mu^+\mu^-
por: de Deboeck, H, et al.
Publicado: (1989)

The Batrachian Barf Bowl: An authentic research experience using ecological data from frog diets
por: Larson, Joanna G., et al.
Publicado: (2022)

Viral-Targeted Strategies Against EBV-Associated Lymphoproliferative Diseases
por: Hui, Kwai Fung, et al.
Publicado: (2019)

DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas
por: Zhu, Xizhou, et al.
Publicado: (2021)

Secretion of Epstein-Barr Virus-encoded BARF1 oncoprotein from latently infected B cells
por: Fiorini, Sylvie, et al.
Publicado: (2008)

The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers
por: Velapasamy, Sharmila, et al.
Publicado: (2018)

Progress in Prophylactic and Therapeutic EBV Vaccine Development Based on Molecular Characteristics of EBV Target Antigens
por: Rozman, Marija, et al.
Publicado: (2022)

Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin
por: Chan, King Chi, et al.
Publicado: (2015)

GMP development and preclinical validation of CAR-T cells targeting a lytic EBV antigen for therapy of EBV-associated malignancies
por: Zhang, Xi, et al.
Publicado: (2023)

Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies
por: Choi, Chung King, et al.
Publicado: (2015)

Prognostication of serial post-intensity-modulated radiation therapy undetectable plasma EBV DNA for nasopharyngeal carcinoma
por: Lee, Victor Ho-Fun, et al.
Publicado: (2016)

The fecal microbiome and metabolome differs between dogs fed Bones and Raw Food (BARF) diets and dogs fed commercial diets
por: Schmidt, Milena, et al.
Publicado: (2018)

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells
por: Zhang, Guitao, et al.
Publicado: (2013)

Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies
Publicado: (1992)

EBV dUTPase: A Novel Modulator of Inflammation and the Tumor Microenvironment in EBV-Associated Malignancies
por: Williams, Marshall V., et al.
Publicado: (2023)

The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism
por: Davis, Alexandra M, et al.
Publicado: (2021)

Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells
por: Kim, Dong Ha, et al.
Publicado: (2016)

Molecular Properties and Therapeutic Targeting of the EBV-Encoded Receptor BILF1
por: Knerr, Julius Maximilian, et al.
Publicado: (2021)

EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis
por: Ma, J, et al.
Publicado: (2016)

Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma
por: Hutajulu, Susanna H, et al.
Publicado: (2010)

Recent Advances on the Possible Neuroprotective Activities of Epstein-Barr Virus Oncogene BARF1 Protein in Chronic Inflammatory Disorders of Central Nervous System
por: Wynne, Alicia, et al.
Publicado: (2010)

Epstein–Barr Virus Gene BARF1 Expression is Regulated by the Epithelial Differentiation Factor ΔNp63α in Undifferentiated Nasopharyngeal Carcinoma
por: Hoebe, Eveline, et al.
Publicado: (2018)

The Methylation Status and Expression of Epstein-Barr Virus Early Genes BARF1 and BHRF1 in Epstein-Barr Virus-Associated Gastric Carcinomas
por: Li, Jing, et al.
Publicado: (2017)

Therapies based on targeting Epstein‐Barr virus lytic replication for EBV‐associated malignancies
por: Li, Hongde, et al.
Publicado: (2018)

mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma
por: Zhang, Jun, et al.
Publicado: (2019)

The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation
por: Shah, Khilan M., et al.
Publicado: (2009)

Vasculogenic mimicry formation in EBV-associated epithelial malignancies
por: Xiang, Tong, et al.
Publicado: (2018)

CD44+ Cancer Stem-Like Cells in EBV-Associated Nasopharyngeal Carcinoma
por: Lun, Samantha Wei-Man, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_1uv9eh99m1bi7f30kqjrtqhja2