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Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes
PURPOSE: To investigate the intraocular distribution and kinetics of antibodies and nanoparticles in the experimental model. METHODS: Antibodies (whole IgG 149kDa, antigen-binding fragments 48.39 kDa) and four kinds of nondegradable nanoparticles (25, 50, 200, and 250 nm) were intravitreally injecte...
Autores principales: | Kim, Hyeong Min, Ha, Seungmin, Hong, Hye Kyoung, Hwang, Yoonha, Kim, Pilhan, Yang, Eunsol, Chung, Jae Yong, Park, Sunyoung, Park, Young Joo, Park, Kyu Hyung, Kim, Hyuncheol, Woo, Se Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409074/ https://www.ncbi.nlm.nih.gov/pubmed/32821517 http://dx.doi.org/10.1167/tvst.9.6.20 |
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