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Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid
Hürthle cell carcinomas (HCC) are rare differentiated thyroid cancers that display low avidity for radioactive iodine and respond poorly to kinase inhibitors. Here, using next-generation sequencing, we analyzed the mutational status of primary tissue and poorly differentiated metastatic tissue from...
Autores principales: | Pecce, Valeria, Verrienti, Antonella, Abballe, Luana, Carletti, Raffaella, Grani, Giorgio, Falcone, Rosa, Ramundo, Valeria, Durante, Cosimo, Di Gioia, Cira, Russo, Diego, Filetti, Sebastiano, Sponziello, Marialuisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409075/ https://www.ncbi.nlm.nih.gov/pubmed/32674319 http://dx.doi.org/10.3390/cancers12071892 |
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