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Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid

Hürthle cell carcinomas (HCC) are rare differentiated thyroid cancers that display low avidity for radioactive iodine and respond poorly to kinase inhibitors. Here, using next-generation sequencing, we analyzed the mutational status of primary tissue and poorly differentiated metastatic tissue from...

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Detalles Bibliográficos
Autores principales: Pecce, Valeria, Verrienti, Antonella, Abballe, Luana, Carletti, Raffaella, Grani, Giorgio, Falcone, Rosa, Ramundo, Valeria, Durante, Cosimo, Di Gioia, Cira, Russo, Diego, Filetti, Sebastiano, Sponziello, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409075/
https://www.ncbi.nlm.nih.gov/pubmed/32674319
http://dx.doi.org/10.3390/cancers12071892

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