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Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI–IM–MS/MS Assay
The third-generation tyrosine kinase inhibitor (TKI), osimertinib, has revolutionized the treatment of patients with non-small cell lung carcinoma with epidermal growth factor receptor (EGFR)-activating mutation, and resistant to first- and second-generation TKIs. Osimertinib is now also proposed as...
Autores principales: | Fresnais, Margaux, Roth, André, Foerster, Kathrin I., Jäger, Dirk, Pfister, Stefan M., Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409122/ https://www.ncbi.nlm.nih.gov/pubmed/32674434 http://dx.doi.org/10.3390/cancers12071897 |
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