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Blocking Notch-Signaling Increases Neurogenesis in the Striatum after Stroke

Stroke triggers neurogenesis in the striatum in mice, with new neurons deriving in part from the nearby subventricular zone and in part from parenchymal astrocytes. The initiation of neurogenesis by astrocytes within the striatum is triggered by reduced Notch-signaling, and blocking this signaling p...

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Detalles Bibliográficos
Autores principales: Santopolo, Giuseppe, Magnusson, Jens P., Lindvall, Olle, Kokaia, Zaal, Frisén, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409130/
https://www.ncbi.nlm.nih.gov/pubmed/32698472
http://dx.doi.org/10.3390/cells9071732

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