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Blocking Notch-Signaling Increases Neurogenesis in the Striatum after Stroke
Stroke triggers neurogenesis in the striatum in mice, with new neurons deriving in part from the nearby subventricular zone and in part from parenchymal astrocytes. The initiation of neurogenesis by astrocytes within the striatum is triggered by reduced Notch-signaling, and blocking this signaling p...
Autores principales: | Santopolo, Giuseppe, Magnusson, Jens P., Lindvall, Olle, Kokaia, Zaal, Frisén, Jonas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409130/ https://www.ncbi.nlm.nih.gov/pubmed/32698472 http://dx.doi.org/10.3390/cells9071732 |
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