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Investigating the Effect of Esterification on Retinal Pigment Epithelial Uptake Using Rhodamine B Derivatives

PURPOSE: This study investigated the effects of esterification and increased lipophilicity on cellular penetration, accumulation and retention in ARPE-19-nic cells using ester functionalized rhodamine B dyes. METHODS: Rhodamine B was esterified to generate four dyes with increasing lipophilicity. Ce...

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Detalles Bibliográficos
Autores principales: Bulumulla, Chandima, Kularatne, Ruvanthi N., Catchpole, Timothy, Takacs, Alison, Christie, Abigail, Gilfoyle, Alexa, Nguyen, Timothy D., Stefan, Mihaela C., Csaky, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409196/
https://www.ncbi.nlm.nih.gov/pubmed/32821515
http://dx.doi.org/10.1167/tvst.9.6.18