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Investigating the Effect of Esterification on Retinal Pigment Epithelial Uptake Using Rhodamine B Derivatives
PURPOSE: This study investigated the effects of esterification and increased lipophilicity on cellular penetration, accumulation and retention in ARPE-19-nic cells using ester functionalized rhodamine B dyes. METHODS: Rhodamine B was esterified to generate four dyes with increasing lipophilicity. Ce...
Autores principales: | Bulumulla, Chandima, Kularatne, Ruvanthi N., Catchpole, Timothy, Takacs, Alison, Christie, Abigail, Gilfoyle, Alexa, Nguyen, Timothy D., Stefan, Mihaela C., Csaky, Karl G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409196/ https://www.ncbi.nlm.nih.gov/pubmed/32821515 http://dx.doi.org/10.1167/tvst.9.6.18 |
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