The Ubiquitin Proteasome System in Hematological Malignancies: New Insight into Its Functional Role and Therapeutic Options

The ubiquitin proteasome system (UPS) is the main cellular degradation machinery designed for controlling turnover of critical proteins involved in cancer pathogenesis, including hematological malignancies. UPS plays a functional role in regulating turnover of key proteins involved in cell cycle arr...

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Detalles Bibliográficos
Autores principales: Di Costanzo, Antonella, Del Gaudio, Nunzio, Conte, Lidio, Altucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409207/
https://www.ncbi.nlm.nih.gov/pubmed/32674429
http://dx.doi.org/10.3390/cancers12071898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409207/
https://www.ncbi.nlm.nih.gov/pubmed/32674429
http://dx.doi.org/10.3390/cancers12071898

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