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The Ubiquitin Proteasome System in Hematological Malignancies: New Insight into Its Functional Role and Therapeutic Options
The ubiquitin proteasome system (UPS) is the main cellular degradation machinery designed for controlling turnover of critical proteins involved in cancer pathogenesis, including hematological malignancies. UPS plays a functional role in regulating turnover of key proteins involved in cell cycle arr...
Autores principales: | Di Costanzo, Antonella, Del Gaudio, Nunzio, Conte, Lidio, Altucci, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409207/ https://www.ncbi.nlm.nih.gov/pubmed/32674429 http://dx.doi.org/10.3390/cancers12071898 |
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