Combinatorial Nanomedicine Made of Squalenoyl-Gemcitabine and Edelfosine for the Treatment of Osteosarcoma

Due to chemoresistance and a high propensity to form lung metastasis, survival rates in pediatric osteosarcoma (OS) are poor. With the aim to improve anticancer activity in pediatric OS, a multidrug nanomedicine was designed using the alkyl-lysophospholipid edelfosine (EF) co-assembled with squaleno...

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Detalles Bibliográficos
Autores principales: Rodríguez-Nogales, Carlos, Moreno, Haritz, Zandueta, Carolina, Desmaële, Didier, Lecanda, Fernando, Couvreur, Patrick, Blanco-Prieto, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409287/
https://www.ncbi.nlm.nih.gov/pubmed/32674353
http://dx.doi.org/10.3390/cancers12071895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409287/
https://www.ncbi.nlm.nih.gov/pubmed/32674353
http://dx.doi.org/10.3390/cancers12071895

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