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MHC Class I Downregulation in Cancer: Underlying Mechanisms and Potential Targets for Cancer Immunotherapy

In recent years, major advances have been made in cancer immunotherapy. This has led to significant improvement in prognosis of cancer patients, especially in the hematological setting. Nonetheless, translation of these successes to solid tumors was found difficult. One major mechanism through which...

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Detalles Bibliográficos
Autores principales: Cornel, Annelisa M., Mimpen, Iris L., Nierkens, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409324/
https://www.ncbi.nlm.nih.gov/pubmed/32630675
http://dx.doi.org/10.3390/cancers12071760