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Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation

Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules. Previously it has been shown that ceramide synthase 6 and 2 influence colitis in several animal mo...

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Detalles Bibliográficos
Autores principales: El-Hindi, Khadija, Brachtendorf, Sebastian, Hartel, Jennifer Christina, Oertel, Stephanie, Birod, Kerstin, Trautmann, Sandra, Thomas, Dominique, Ulshöfer, Thomas, Weigert, Andreas, Utermöhlen, Olaf, Krönke, Martin, Grösch, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409364/
https://www.ncbi.nlm.nih.gov/pubmed/32630271
http://dx.doi.org/10.3390/cancers12071753