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Hypoxia alleviates dexamethasone-induced inhibition of angiogenesis in cocultures of HUVECs and rBMSCs via HIF-1α

BACKGROUND AND AIM: Inadequate vascularization is a challenge in bone tissue engineering because internal cells are prone to necrosis due to a lack of nutrient supply. Rat bone marrow-derived mesenchymal stem cells (rBMSCs) and human umbilical vein endothelial cells (HUVECs) were cocultured to const...

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Detalles Bibliográficos
Autores principales:	Chai, Miaomiao, Gu, Ce, Shen, Qihua, Liu, Jiaxing, Zhou, Yi, Jin, Ziyang, Xiong, Wanli, Zhou, Yan, Tan, Wensong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409505/ https://www.ncbi.nlm.nih.gov/pubmed/32762747 http://dx.doi.org/10.1186/s13287-020-01853-x

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