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COVID-19: data-driven dynamics, statistical and distributed delay models, and observations

COVID-19 was declared as a pandemic by the World Health Organization on March 11, 2020. Here, the dynamics of this epidemic is studied by using a generalized logistic function model and extended compartmental models with and without delays. For a chosen population, it is shown as to how forecasting...

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Autores principales: Liu, Xianbo, Zheng, Xie, Balachandran, Balakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409621/
https://www.ncbi.nlm.nih.gov/pubmed/32836818
http://dx.doi.org/10.1007/s11071-020-05863-5
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author Liu, Xianbo
Zheng, Xie
Balachandran, Balakumar
author_facet Liu, Xianbo
Zheng, Xie
Balachandran, Balakumar
author_sort Liu, Xianbo
collection PubMed
description COVID-19 was declared as a pandemic by the World Health Organization on March 11, 2020. Here, the dynamics of this epidemic is studied by using a generalized logistic function model and extended compartmental models with and without delays. For a chosen population, it is shown as to how forecasting may be done on the spreading of the infection by using a generalized logistic function model, which can be interpreted as a basic compartmental model. In an extended compartmental model, which is a modified form of the SEIQR model, the population is divided into susceptible, exposed, infectious, quarantined, and removed (recovered or dead) compartments, and a set of delay integral equations is used to describe the system dynamics. Time-varying infection rates are allowed in the model to capture the responses to control measures taken, and distributed delay distributions are used to capture variability in individual responses to an infection. The constructed extended compartmental model is a nonlinear dynamical system with distributed delays and time-varying parameters. The critical role of data is elucidated, and it is discussed as to how the compartmental model can be used to capture responses to various measures including quarantining. Data for different parts of the world are considered, and comparisons are also made in terms of the reproductive number. The obtained results can be useful for furthering the understanding of disease dynamics as well as for planning purposes.
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spelling pubmed-74096212020-08-07 COVID-19: data-driven dynamics, statistical and distributed delay models, and observations Liu, Xianbo Zheng, Xie Balachandran, Balakumar Nonlinear Dyn Original Paper COVID-19 was declared as a pandemic by the World Health Organization on March 11, 2020. Here, the dynamics of this epidemic is studied by using a generalized logistic function model and extended compartmental models with and without delays. For a chosen population, it is shown as to how forecasting may be done on the spreading of the infection by using a generalized logistic function model, which can be interpreted as a basic compartmental model. In an extended compartmental model, which is a modified form of the SEIQR model, the population is divided into susceptible, exposed, infectious, quarantined, and removed (recovered or dead) compartments, and a set of delay integral equations is used to describe the system dynamics. Time-varying infection rates are allowed in the model to capture the responses to control measures taken, and distributed delay distributions are used to capture variability in individual responses to an infection. The constructed extended compartmental model is a nonlinear dynamical system with distributed delays and time-varying parameters. The critical role of data is elucidated, and it is discussed as to how the compartmental model can be used to capture responses to various measures including quarantining. Data for different parts of the world are considered, and comparisons are also made in terms of the reproductive number. The obtained results can be useful for furthering the understanding of disease dynamics as well as for planning purposes. Springer Netherlands 2020-08-06 2020 /pmc/articles/PMC7409621/ /pubmed/32836818 http://dx.doi.org/10.1007/s11071-020-05863-5 Text en © Springer Nature B.V. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Liu, Xianbo
Zheng, Xie
Balachandran, Balakumar
COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title_full COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title_fullStr COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title_full_unstemmed COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title_short COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
title_sort covid-19: data-driven dynamics, statistical and distributed delay models, and observations
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409621/
https://www.ncbi.nlm.nih.gov/pubmed/32836818
http://dx.doi.org/10.1007/s11071-020-05863-5
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AT balachandranbalakumar covid19datadrivendynamicsstatisticalanddistributeddelaymodelsandobservations