N-acetylcysteine alleviates post-resuscitation myocardial dysfunction and improves survival outcomes via partly inhibiting NLRP3 inflammasome induced-pyroptosis

BACKGROUND: NOD-like receptor 3 (NLRP3) inflammasome is necessary to initiate acute sterile inflammation. Increasing evidence indicates the activation of NLRP3 inflammasome induced pyroptosis is closely related to reactive oxygen species (ROS) in the sterile inflammatory response triggered by ischem...

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Detalles Bibliográficos
Autores principales: He, Fenglian, Zheng, Guanghui, Hou, Jingying, Hu, Qiaohua, Ling, Qin, Wu, Gongfa, Zhao, Hui, Yang, Jin, Wang, Yue, Jiang, Longyuan, Tang, Wanchun, Yang, Zhengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409674/
https://www.ncbi.nlm.nih.gov/pubmed/32782443
http://dx.doi.org/10.1186/s12950-020-00255-3

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