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A multi-centre, double-blind, 12-week, randomized, placebo-controlled trial to assess the efficacy of adjunctive N-Acetylcysteine for treatment-resistant PTSD: a study protocol

BACKGROUND: Most patients with Posttraumatic Stress Disorder (PTSD) suffer residual symptoms following first-line treatment. Oxidative stress has been implicated in the pathophysiology of PTSD. N-acetylcysteine (NAC) is a precursor of the brain’s primary antioxidant, glutathione, and may diminish ox...

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Detalles Bibliográficos
Autores principales:	Maier, Alice, Dharan, Anita, Oliver, Gina, Berk, Michael, Redston, Suzy, Back, Sudie E., Kalivas, Peter, Ng, Chee, Kanaan, Richard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409699/ https://www.ncbi.nlm.nih.gov/pubmed/32762663 http://dx.doi.org/10.1186/s12888-020-02793-9

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