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Time-series analyses of directional sequence changes in SARS-CoV-2 genomes and an efficient search method for candidates for advantageous mutations for growth in human cells

We first conducted time-series analysis of mono- and dinucleotide composition for over 10,000 SARS-CoV-2 genomes, as well as over 1500 Zaire ebolavirus genomes, and found clear time-series changes in the compositions on a monthly basis, which should reflect viral adaptations for efficient growth in...

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Detalles Bibliográficos
Autores principales: Wada, Kennosuke, Wada, Yoshiko, Ikemura, Toshimichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409725/
https://www.ncbi.nlm.nih.gov/pubmed/32835214
http://dx.doi.org/10.1016/j.gene.2020.100038

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