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Extended experimental inferential structure determination method in determining the structural ensembles of disordered protein states

Proteins with intrinsic or unfolded state disorder comprise a new frontier in structural biology, requiring the characterization of diverse and dynamic structural ensembles. Here we introduce a comprehensive Bayesian framework, the Extended Experimental Inferential Structure Determination (X-EISD) m...

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Detalles Bibliográficos
Autores principales: Lincoff, James, Haghighatlari, Mojtaba, Krzeminski, Mickael, Teixeira, João M. C., Gomes, Gregory-Neal W., Gradinaru, Claudiu C., Forman-Kay, Julie D., Head-Gordon, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409953/
https://www.ncbi.nlm.nih.gov/pubmed/32775701
http://dx.doi.org/10.1038/s42004-020-0323-0