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Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations

CD4+ T cells play an important role in the maturation of the antibody responses. Conjugation of identified CD4+ T cell helper epitope to the target antigen has been developed as a strategy to enhance vaccine-induced humoral immunity. In this work, we reported the identification of a novel HLA-IAb he...

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Detalles Bibliográficos
Autores principales:	Xu, Ziyang, Chokkalingam, Neethu, Tello-Ruiz, Edgar, Walker, Susanne, Kulp, Daniel W., Weiner, David B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409978/ https://www.ncbi.nlm.nih.gov/pubmed/32763137 http://dx.doi.org/10.1016/j.isci.2020.101399

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