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Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC

BACKGROUND: The aim of this survey was to acquire an overview of the current management of ovarian cancer with an emphasis on the utility of hyperthermic intraperitoneal chemotherapy (HIPEC). Methods: An email was sent to Oncologists prior to PSOGI International Symposium on Advanced Ovarian Cancer,...

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Autores principales: Iavazzo, Christos, Fotiou, Alexandros, Tsiatas, M., Christopoulou, Athina, Spiliotis, John, Sugarbaker, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410114/
https://www.ncbi.nlm.nih.gov/pubmed/32821775
http://dx.doi.org/10.1515/pp-2019-0029
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author Iavazzo, Christos
Fotiou, Alexandros
Tsiatas, M.
Christopoulou, Athina
Spiliotis, John
Sugarbaker, Paul
author_facet Iavazzo, Christos
Fotiou, Alexandros
Tsiatas, M.
Christopoulou, Athina
Spiliotis, John
Sugarbaker, Paul
author_sort Iavazzo, Christos
collection PubMed
description BACKGROUND: The aim of this survey was to acquire an overview of the current management of ovarian cancer with an emphasis on the utility of hyperthermic intraperitoneal chemotherapy (HIPEC). Methods: An email was sent to Oncologists prior to PSOGI International Symposium on Advanced Ovarian Cancer, Athens 11–13 April 2019. Doctors submitted responses on the relevant website. The self-report survey contained 17 questions. RESULTS: In total, 467 Medical Oncologists, Surgical Oncologists or Gynaecologic Oncologists were participated and answered to this survey. The resectability of disease was evaluated by laparoscopy from 48.5% of the participants, while 51.5% answered that they stage their patients pre-surgically with the use of CT or MRI. The preferred first intervention in advanced ovarian cancer patients is the neoadjuvant chemotherapy followed by interval cytoreductive surgery (72%). Regarding the use of HIPEC, almost half of the participants answered that there is role of HIPEC use in ovarian cancer patients undergoing interval debulking surgery, while almost 70% answered positively about the utility of HIPEC use in ovarian cancer recurrence. As for the role of lymphadenectomy in advanced ovarian cancer patients, half of the responders answered negatively. Finally, only 25% of the participants responded that they always check the BRCA status of their ovarian cancer patients, despite the possible differentiation of treatment based on the molecular profiling (80%). CONCLUSIONS: The results of this survey indicate the utility of HIPEC in treatment of ovarian cancer patients and the differences in the overall management of ovarian cancer patients in the current clinical practice.
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spelling pubmed-74101142020-08-19 Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC Iavazzo, Christos Fotiou, Alexandros Tsiatas, M. Christopoulou, Athina Spiliotis, John Sugarbaker, Paul Pleura Peritoneum Research Article BACKGROUND: The aim of this survey was to acquire an overview of the current management of ovarian cancer with an emphasis on the utility of hyperthermic intraperitoneal chemotherapy (HIPEC). Methods: An email was sent to Oncologists prior to PSOGI International Symposium on Advanced Ovarian Cancer, Athens 11–13 April 2019. Doctors submitted responses on the relevant website. The self-report survey contained 17 questions. RESULTS: In total, 467 Medical Oncologists, Surgical Oncologists or Gynaecologic Oncologists were participated and answered to this survey. The resectability of disease was evaluated by laparoscopy from 48.5% of the participants, while 51.5% answered that they stage their patients pre-surgically with the use of CT or MRI. The preferred first intervention in advanced ovarian cancer patients is the neoadjuvant chemotherapy followed by interval cytoreductive surgery (72%). Regarding the use of HIPEC, almost half of the participants answered that there is role of HIPEC use in ovarian cancer patients undergoing interval debulking surgery, while almost 70% answered positively about the utility of HIPEC use in ovarian cancer recurrence. As for the role of lymphadenectomy in advanced ovarian cancer patients, half of the responders answered negatively. Finally, only 25% of the participants responded that they always check the BRCA status of their ovarian cancer patients, despite the possible differentiation of treatment based on the molecular profiling (80%). CONCLUSIONS: The results of this survey indicate the utility of HIPEC in treatment of ovarian cancer patients and the differences in the overall management of ovarian cancer patients in the current clinical practice. De Gruyter 2020-02-26 /pmc/articles/PMC7410114/ /pubmed/32821775 http://dx.doi.org/10.1515/pp-2019-0029 Text en © 2020 Iavazzo et al., published by De Gruyter http://creativecommons.org/licenses/by/4.0 This work is licensed under the Creative Commons Attribution 4.0 Public License.
spellingShingle Research Article
Iavazzo, Christos
Fotiou, Alexandros
Tsiatas, M.
Christopoulou, Athina
Spiliotis, John
Sugarbaker, Paul
Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title_full Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title_fullStr Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title_full_unstemmed Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title_short Survey on the current gynaecological approach of ovarian cancer patients: The utility of HIPEC
title_sort survey on the current gynaecological approach of ovarian cancer patients: the utility of hipec
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410114/
https://www.ncbi.nlm.nih.gov/pubmed/32821775
http://dx.doi.org/10.1515/pp-2019-0029
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