Cargando…
Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost?
BACKGROUND: Chickenpox is a highly contagious airborne disease caused by the varicella zoster virus. It is generally benign and self-limiting, but it may be responsible of life-threatening complications. Acute cerebellitis (AC) is the most common neurological complication and is associated with prol...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410155/ https://www.ncbi.nlm.nih.gov/pubmed/32762761 http://dx.doi.org/10.1186/s13052-020-00875-8 |
_version_ | 1783568184719179776 |
---|---|
author | Bozzola, Elena Guolo, Stefano Macchiarulo, Giulia Festa, Lidia Spina, Giulia Krzysztofiak, Andrzej Grandin, Annalisa Bozzola, Mauro Raponi, Massimiliano Villani, Alberto |
author_facet | Bozzola, Elena Guolo, Stefano Macchiarulo, Giulia Festa, Lidia Spina, Giulia Krzysztofiak, Andrzej Grandin, Annalisa Bozzola, Mauro Raponi, Massimiliano Villani, Alberto |
author_sort | Bozzola, Elena |
collection | PubMed |
description | BACKGROUND: Chickenpox is a highly contagious airborne disease caused by the varicella zoster virus. It is generally benign and self-limiting, but it may be responsible of life-threatening complications. Acute cerebellitis (AC) is the most common neurological complication and is associated with prolonged hospitalization in the acute phase (HAP). AIM OF THE STUDY: To estimate the costs of AC HAP in children affected by varicella. MATERIALS AND METHODS: We retrospectively reviewed the medical records of a pediatric cohort hospitalized for chickenpox AC over a period of 15 years (from October 2003 to October 2018) and we analyzed acute care costs. For any patient the HAP has been calculated. The final value includes cost of hospital accommodation and management at the Pediatric and Infectious Diseases Unit. To this cost, the price of procedures (imaging, laboratory exams, medical and paramedical evaluations) and medical treatments was added. RESULTS: In the study period, 856 children had been hospitalized for varicella. Out of them, 65 met a diagnosis of AC and were included in the study. The hospitalization length was of 10 days (range 3–20 days). The median cost of HAP for each patient was of 5366 euro, with an average annual cost of 23,252 €. The most significant part of HAP is due to the cost of hospital accommodation and management at the Pediatric Infectious Diseases Unit, which was about € 537.78 for a single day. DISCUSSION: Although AC post-varicella is rare, its HAP cost is not negligible resulting in substantial economic burden. Vaccination would have probably prevented varicella and AC complication, avoiding hospitalization. CONCLUSIONS: Financial studies are important for evaluate the cost saving in order to influence public funding decisions. Further studies are necessary to investigate the economic burden of the disease. |
format | Online Article Text |
id | pubmed-7410155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-74101552020-08-10 Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? Bozzola, Elena Guolo, Stefano Macchiarulo, Giulia Festa, Lidia Spina, Giulia Krzysztofiak, Andrzej Grandin, Annalisa Bozzola, Mauro Raponi, Massimiliano Villani, Alberto Ital J Pediatr Research BACKGROUND: Chickenpox is a highly contagious airborne disease caused by the varicella zoster virus. It is generally benign and self-limiting, but it may be responsible of life-threatening complications. Acute cerebellitis (AC) is the most common neurological complication and is associated with prolonged hospitalization in the acute phase (HAP). AIM OF THE STUDY: To estimate the costs of AC HAP in children affected by varicella. MATERIALS AND METHODS: We retrospectively reviewed the medical records of a pediatric cohort hospitalized for chickenpox AC over a period of 15 years (from October 2003 to October 2018) and we analyzed acute care costs. For any patient the HAP has been calculated. The final value includes cost of hospital accommodation and management at the Pediatric and Infectious Diseases Unit. To this cost, the price of procedures (imaging, laboratory exams, medical and paramedical evaluations) and medical treatments was added. RESULTS: In the study period, 856 children had been hospitalized for varicella. Out of them, 65 met a diagnosis of AC and were included in the study. The hospitalization length was of 10 days (range 3–20 days). The median cost of HAP for each patient was of 5366 euro, with an average annual cost of 23,252 €. The most significant part of HAP is due to the cost of hospital accommodation and management at the Pediatric Infectious Diseases Unit, which was about € 537.78 for a single day. DISCUSSION: Although AC post-varicella is rare, its HAP cost is not negligible resulting in substantial economic burden. Vaccination would have probably prevented varicella and AC complication, avoiding hospitalization. CONCLUSIONS: Financial studies are important for evaluate the cost saving in order to influence public funding decisions. Further studies are necessary to investigate the economic burden of the disease. BioMed Central 2020-08-06 /pmc/articles/PMC7410155/ /pubmed/32762761 http://dx.doi.org/10.1186/s13052-020-00875-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Bozzola, Elena Guolo, Stefano Macchiarulo, Giulia Festa, Lidia Spina, Giulia Krzysztofiak, Andrzej Grandin, Annalisa Bozzola, Mauro Raponi, Massimiliano Villani, Alberto Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title | Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title_full | Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title_fullStr | Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title_full_unstemmed | Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title_short | Hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
title_sort | hospitalization for acute cerebellitis in children affected by varicella: how much does it cost? |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410155/ https://www.ncbi.nlm.nih.gov/pubmed/32762761 http://dx.doi.org/10.1186/s13052-020-00875-8 |
work_keys_str_mv | AT bozzolaelena hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT guolostefano hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT macchiarulogiulia hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT festalidia hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT spinagiulia hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT krzysztofiakandrzej hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT grandinannalisa hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT bozzolamauro hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT raponimassimiliano hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost AT villanialberto hospitalizationforacutecerebellitisinchildrenaffectedbyvaricellahowmuchdoesitcost |