Cargando…

Genome-wide methylation patterns predict clinical benefit of immunotherapy in lung cancer

BACKGROUND: It is crucial to unravel molecular determinants of responses to immune checkpoint blockade (ICB) therapy because only a small subset of advanced non-small cell lung cancer (NSCLC) patients responds to ICB therapy. Previous studies were concentrated on genomic and transcriptomic markers (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jeong Yeon, Choi, Jung Kyoon, Jung, Hyunchul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410160/ https://www.ncbi.nlm.nih.gov/pubmed/32762727 http://dx.doi.org/10.1186/s13148-020-00907-4

Ejemplares similares

Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity
por: Kim, Kwoneel, et al.
Publicado: (2020)

Genome-wide DNA methylation signature predict clinical benefit of bevacizumab in non-small cell lung cancer
por: Li, Butuo, et al.
Publicado: (2022)

Genome-wide analysis of DNA methylation patterns in horse
por: Lee, Ja-Rang, et al.
Publicado: (2014)

Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer
por: Hwang, Sohyun, et al.
Publicado: (2020)

DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
por: Jung, Hyunchul, et al.
Publicado: (2019)

DeepNeo: a webserver for predicting immunogenic neoantigens
por: Kim, Jeong Yeon, et al.
Publicado: (2023)

Estimating genome-wide DNA methylation heterogeneity with methylation patterns
por: Lin, Pei-Yu, et al.
Publicado: (2023)

Genome-wide methylation patterns in Marfan syndrome
por: van Andel, Mitzi M., et al.
Publicado: (2021)

Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma
por: Lietz, Christopher E., et al.
Publicado: (2022)

Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers
por: Jung, Hyunchul, et al.
Publicado: (2018)

Comprehensive characterisation of intronic mis-splicing mutations in human cancers
por: Jung, Hyunchul, et al.
Publicado: (2021)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

Genome-wide quantitative assessment of variation in DNA methylation patterns
por: Xie, Hehuang, et al.
Publicado: (2011)

Genome-wide quantitative assessment of variation in DNA methylation patterns
por: Xie, H., et al.
Publicado: (2013)

Genome-Wide Discriminatory Information Patterns of Cytosine DNA Methylation
por: Sanchez, Robersy, et al.
Publicado: (2016)

Differential genome-wide DNA methylation patterns in childhood obesity
por: Cao-Lei, Lei, et al.
Publicado: (2019)

Genome-wide methylation patterns from canine nanopore assemblies
por: Schall, Peter Z, et al.
Publicado: (2023)

A long-range interactive DNA methylation marker panel for the promoters of HOXA9 and HOXA10 predicts survival in breast cancer patients
por: Park, Seong-Min, et al.
Publicado: (2017)

Contrasting chromatin organization of CpG islands and exons in the human genome
por: Choi, Jung Kyoon
Publicado: (2010)

Variation in Genotype and DNA Methylation Patterns Based on Alcohol Use and CVD in the Korean Genome and Epidemiology Study (KoGES)
por: Jung, Myoungjee, et al.
Publicado: (2022)

Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation
por: Seo, Jungmin, et al.
Publicado: (2014)

DNA methylation profiling in early lung adenocarcinoma to predict response to immunotherapy
por: De Smet, Charles
Publicado: (2023)

Prediction of genome-wide DNA methylation in repetitive elements
por: Zheng, Yinan, et al.
Publicado: (2017)

Comprehensive analysis of blood-based biomarkers for predicting immunotherapy benefits in patients with advanced non-small cell lung cancer
por: Park, Cheol-Kyu, et al.
Publicado: (2021)

Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
por: Sahu, Avinash Das, et al.
Publicado: (2019)

Granzyme B for predicting the durable clinical benefit of anti-PD-1/PD-L1 immunotherapy in patients with non-small cell lung cancer
por: Chung, Jae Heun, et al.
Publicado: (2022)

Data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of DNA methylation in lung tissues
por: Fish, Trevor J., et al.
Publicado: (2017)

Maternal Genome-Wide DNA Methylation Patterns and Congenital Heart Defects
por: Chowdhury, Shimul, et al.
Publicado: (2011)

Genome-Wide Methylation Patterns in Salmonella enterica Subsp. enterica Serovars
por: Pirone-Davies, Cary, et al.
Publicado: (2015)

Genome-Wide DNA Methylation Patterns and Transcription Analysis in Sheep Muscle
por: Couldrey, Christine, et al.
Publicado: (2014)

Genome-wide DNA methylation patterns associated with general psychopathology in children
por: Rijlaarsdam, Jolien, et al.
Publicado: (2021)

Nucleosome deposition and DNA methylation at coding region boundaries
por: Choi, Jung Kyoon, et al.
Publicado: (2009)

Genomic Sequencing for Bladder Urothelial Carcinoma and Its Clinical Implications for Immunotherapy
por: Kim, Ryul, et al.
Publicado: (2022)

Global DNA Methylation in the Chestnut Blight Fungus Cryphonectria parasitica and Genome-Wide Changes in DNA Methylation Accompanied with Sectorization
por: So, Kum-Kang, et al.
Publicado: (2018)

Genome-wide DNA methylation profiling reveals candidate biomarkers and probable molecular mechanism of metabolic syndrome
por: Baek, Su-Jin, et al.
Publicado: (2022)

Genome-wide DNA methylation profiling in a rat model with vascular dementia
por: Park, Jong-Min, et al.
Publicado: (2018)

Phenotype prediction based on genome-wide DNA methylation data
por: Wilhelm, Thomas
Publicado: (2014)

Relationship of the lung microbiome with PD-L1 expression and immunotherapy response in lung cancer
por: Jang, Hye Jin, et al.
Publicado: (2021)

Stochastic and Regulatory Role of Chromatin Silencing in Genomic Response to Environmental Changes
por: Choi, Jung Kyoon, et al.
Publicado: (2008)

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
por: Zhang, Weiwei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mo3v6bv0dcfnoeargiiij3g7nq