Gene design, optimization of protein expression and preliminary evaluation of a new chimeric protein for the serological diagnosis of both human and canine visceral leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) is a major neglected disease, potentially fatal, whose control is still impaired by inefficient and/or expensive treatment and diagnostic methods. The most promising approach for VL diagnosis uses serological assays with recombinant proteins, since they are mo...

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Detalles Bibliográficos
Autores principales: Santos, Wagner J. T., Tavares, Diego H. C., Castro Neto, Artur L., Nascimento, Marília B., Dhalia, Rafael, Albuquerque, Alessandra L., Costa, Carlos H. N., Magalhães, Franklin B., Rezende, Antônio M., de Melo Neto, Osvaldo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410341/
https://www.ncbi.nlm.nih.gov/pubmed/32716931
http://dx.doi.org/10.1371/journal.pntd.0008488

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