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Revisiting NTRKs as an emerging oncogene in hematological malignancies
NTRK fusions are dominant oncogenic drivers found in rare solid tumors. These fusions have also been identified in more common cancers, such as lung and colorectal carcinomas, albeit at low frequencies. Patients harboring these fusions demonstrate significant clinical response to inhibitors such as...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410820/ https://www.ncbi.nlm.nih.gov/pubmed/31551508 http://dx.doi.org/10.1038/s41375-019-0576-8 |