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Elevation in the counts of IL-35-producing B cells infiltrating into lung tissue in mycobacterial infection is associated with the downregulation of Th1/Th17 and upregulation of Foxp3(+)Treg

IL-35 is an anti-inflammatory cytokine and is thought to be produced by regulatory T (Treg) cells. A previous study found that IL-35 was upregulated in the serum of patients with active tuberculosis (ATB), and IL-35-producing B cells infiltrated to tuberculous granuloma of patients with ATB. Purifie...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Xu, Huan, Peng, Ying, Luo, Hong, Huang, Gui-Xian, Wu, Xian-Jin, Dai, You-Chao, Luo, Hou-Long, Zhang, Jun-Ai, Zheng, Bi-Ying, Zhang, Xiang-Ning, Chen, Zheng W., Xu, Jun-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411070/
https://www.ncbi.nlm.nih.gov/pubmed/32764544
http://dx.doi.org/10.1038/s41598-020-69984-y