AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway

Glioblastoma multiforme (GBM) is the most common intracranial malignancy in adults with the highest degree of malignancy and mortality. Due to its nature of diffuse invasiveness and high migration, GBM lacks an effective treatment strategy and is associated with poor prognosis. SC66 is a novel AKT i...

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Detalles Bibliográficos
Autores principales: Gao, Lun, Liu, Junhui, Xu, Pengfei, Deng, Gang, Liu, Baohui, Yuan, Fanen, Tan, Yinqiu, Sun, Qian, Xu, Yang, Zhang, Huikai, Qi, Yangzhi, Han, Shoumeng, Yang, Kun, Geng, Rongxin, Jiang, Hongxiang, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411127/
https://www.ncbi.nlm.nih.gov/pubmed/32848734
http://dx.doi.org/10.3389/fphar.2020.01102

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