High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay

BACKGROUND: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. METHODS: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high‐density activation mapping using a new software called extended early‐meets‐late (EEML). RESULTS: Irrespective of the arrhythm...

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Detalles Bibliográficos
Autores principales: Letsas, Konstantinos P., Efremidis, Michael, Bazoukis, George, Dragasis, Stylianos, Megarisiotou, Athanasia, Mililis, Panagiotis, Saplaouras, Athanasios, Vlachos, Konstantinos, Asvestas, Dimitrios, Valkanas, Kosmas, Tse, Gary, Sideris, Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Rapid Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411206/
https://www.ncbi.nlm.nih.gov/pubmed/32782657
http://dx.doi.org/10.1002/joa3.12380
Descripción
Sumario:BACKGROUND: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. METHODS: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high‐density activation mapping using a new software called extended early‐meets‐late (EEML). RESULTS: Irrespective of the arrhythmia mechanism, low bipolar voltage fractionated signals (0.14 ± 0.10 mV) were seen at the earliest activation site. The mean low‐voltage area (LVA) at the earliest activation site was 3.2 ± 1.0 cm(2). EEML mapping revealed zones of conduction delay at the borders of LVAs. CONCLUSIONS: LVAs protected by zones of slow conduction appears to play an important role in the initiation and maintenance of focal ATs.

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