High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay

BACKGROUND: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. METHODS: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high‐density activation mapping using a new software called extended early‐meets‐late (EEML). RESULTS: Irrespective of the arrhythm...

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Autores principales: Letsas, Konstantinos P., Efremidis, Michael, Bazoukis, George, Dragasis, Stylianos, Megarisiotou, Athanasia, Mililis, Panagiotis, Saplaouras, Athanasios, Vlachos, Konstantinos, Asvestas, Dimitrios, Valkanas, Kosmas, Tse, Gary, Sideris, Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Rapid Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411206/
https://www.ncbi.nlm.nih.gov/pubmed/32782657
http://dx.doi.org/10.1002/joa3.12380
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author Letsas, Konstantinos P.
Efremidis, Michael
Bazoukis, George
Dragasis, Stylianos
Megarisiotou, Athanasia
Mililis, Panagiotis
Saplaouras, Athanasios
Vlachos, Konstantinos
Asvestas, Dimitrios
Valkanas, Kosmas
Tse, Gary
Sideris, Antonios
author_facet Letsas, Konstantinos P.
Efremidis, Michael
Bazoukis, George
Dragasis, Stylianos
Megarisiotou, Athanasia
Mililis, Panagiotis
Saplaouras, Athanasios
Vlachos, Konstantinos
Asvestas, Dimitrios
Valkanas, Kosmas
Tse, Gary
Sideris, Antonios
author_sort Letsas, Konstantinos P.
collection PubMed
description BACKGROUND: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. METHODS: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high‐density activation mapping using a new software called extended early‐meets‐late (EEML). RESULTS: Irrespective of the arrhythmia mechanism, low bipolar voltage fractionated signals (0.14 ± 0.10 mV) were seen at the earliest activation site. The mean low‐voltage area (LVA) at the earliest activation site was 3.2 ± 1.0 cm(2). EEML mapping revealed zones of conduction delay at the borders of LVAs. CONCLUSIONS: LVAs protected by zones of slow conduction appears to play an important role in the initiation and maintenance of focal ATs.
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spelling pubmed-74112062020-08-10 High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay Letsas, Konstantinos P. Efremidis, Michael Bazoukis, George Dragasis, Stylianos Megarisiotou, Athanasia Mililis, Panagiotis Saplaouras, Athanasios Vlachos, Konstantinos Asvestas, Dimitrios Valkanas, Kosmas Tse, Gary Sideris, Antonios J Arrhythm Rapid Communications BACKGROUND: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. METHODS: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high‐density activation mapping using a new software called extended early‐meets‐late (EEML). RESULTS: Irrespective of the arrhythmia mechanism, low bipolar voltage fractionated signals (0.14 ± 0.10 mV) were seen at the earliest activation site. The mean low‐voltage area (LVA) at the earliest activation site was 3.2 ± 1.0 cm(2). EEML mapping revealed zones of conduction delay at the borders of LVAs. CONCLUSIONS: LVAs protected by zones of slow conduction appears to play an important role in the initiation and maintenance of focal ATs. John Wiley and Sons Inc. 2020-06-14 /pmc/articles/PMC7411206/ /pubmed/32782657 http://dx.doi.org/10.1002/joa3.12380 Text en © 2020 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Rapid Communications
Letsas, Konstantinos P.
Efremidis, Michael
Bazoukis, George
Dragasis, Stylianos
Megarisiotou, Athanasia
Mililis, Panagiotis
Saplaouras, Athanasios
Vlachos, Konstantinos
Asvestas, Dimitrios
Valkanas, Kosmas
Tse, Gary
Sideris, Antonios
High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title_full High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title_fullStr High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title_full_unstemmed High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title_short High‐density mapping of de novo focal atrial tachycardias using a new software: Protected low‐voltage areas by zones of conduction delay
title_sort high‐density mapping of de novo focal atrial tachycardias using a new software: protected low‐voltage areas by zones of conduction delay
topic Rapid Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411206/
https://www.ncbi.nlm.nih.gov/pubmed/32782657
http://dx.doi.org/10.1002/joa3.12380
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