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Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1

Molecular responses to genotoxic stress, such as ionizing radiation, are intricately complex and involve hundreds of genes. Whether targeted overexpression of an endogenous gene can enhance resistance to ionizing radiation remains to be explored. In the present study we take an advantage of the CRIS...

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Detalles Bibliográficos
Autores principales: Velegzhaninov, Ilya O., Belykh, Elena S., Rasova, Elena E., Pylina, Yana I., Shadrin, Dmitry M., Klokov, Dmitry Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411226/
https://www.ncbi.nlm.nih.gov/pubmed/32849834
http://dx.doi.org/10.3389/fgene.2020.00855