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Leveraging a Validated in silico Approach to Elucidate Genotype-Specific VP7 Epitopes and Antigenic Relationships of Porcine Rotavirus A

Rotavirus A (RVA) remains one of the most widespread causes of diarrheal disease and mortality in piglets despite decades of research and efforts to boost lactogenic immunity for passive protection. Genetic changes at B cell epitopes (BCEs) may be driving failure of lactogenic immunity, which relies...

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Detalles Bibliográficos
Autores principales: Shepherd, Frances K., Dvorak, Cheryl M. T., Murtaugh, Michael P., Marthaler, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411229/
https://www.ncbi.nlm.nih.gov/pubmed/32849819
http://dx.doi.org/10.3389/fgene.2020.00828