Targeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway

BACKGROUND: Salivary adenoid cystic carcinoma (SACC), a rare cancer arising in the salivary glands, is characterized by high rates of relapse and distant metastasis. Epidermal growth factor receptor (EGFR) has been implicated in SACC carcinogenesis. However, prospective trials of EGFR-targeting ther...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Han, Yong, Xu, Shengming, Zhang, Ling, Zhang, Xiangkai, Deng, Jiong, Ye, Weimin, Liu, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411275/
https://www.ncbi.nlm.nih.gov/pubmed/32801899
http://dx.doi.org/10.2147/CMAR.S253500

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