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Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice
The age-dependent declines of skeletal muscle and cognitive functions often coexist in elderly subjects. The underlying pathophysiological mechanisms share common features of mitochondrial dysfunction, which plays a central role in the development of overt sarcopenia and/or dementia. Dietary supplem...
Autores principales: | Brunetti, Dario, Bottani, Emanuela, Segala, Agnese, Marchet, Silvia, Rossi, Fabio, Orlando, Fiorenza, Malavolta, Marco, Carruba, Michele O., Lamperti, Costanza, Provinciali, Mauro, Nisoli, Enzo, Valerio, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411305/ https://www.ncbi.nlm.nih.gov/pubmed/32848778 http://dx.doi.org/10.3389/fphar.2020.01171 |
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