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Low expression of miR-532-3p contributes to cerebral ischemia/reperfusion oxidative stress injury by directly targeting NOX2

NADPH oxidase 2 (NOX2) is a major subtype of NOX and is responsible for the generation of reactive oxygen species (ROS) in brain tissues. MicroRNAs (miRNAs/miRs) are important epigenetic regulators of NOX2. The present study aimed to identify the role of NOX2 miRNA-targets in ischemic stroke (IS). A...

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Detalles Bibliográficos
Autores principales: Mao, Li, Zuo, Mei-Ling, Wang, Ai-Ping, Tian, Ying, Dong, Li-Chen, Li, Tao-Ming, Kuang, Da-Bin, Song, Gui-Lin, Yang, Zhong-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411405/
https://www.ncbi.nlm.nih.gov/pubmed/32705253
http://dx.doi.org/10.3892/mmr.2020.11325