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Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis

Background. Previous research has shown that peroxiredoxin 1 (Prdx1) is an important modulator of physiological and pathophysiological cardiovascular events. This study is aimed at investigating the role and underlying mechanism of Prdx1 in doxorubicin- (DOX-) induced cardiotoxicity. Cardiac-specifi...

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Detalles Bibliográficos
Autores principales: Jiang, Lai, Gong, Yanping, Hu, Yida, You, Yangyang, Wang, Jiawu, Zhang, Zhetao, Wei, Zeyuan, Tang, Chaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411498/
https://www.ncbi.nlm.nih.gov/pubmed/32802259
http://dx.doi.org/10.1155/2020/2405135